Does tiotropium bromide lead to bronchodilation in cystic fibrosis ?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000728639

Enrollment

Registered

2005-11-11

Start date

2005-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

A single dose of inhaled tiotropium bromide with measurement of FEV1 over the following 24 hours. Then a 7 day 'washout' period follwed by cross-over to the alternate study arm and repeat

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Confirmed CF, stable disease ( no infective exacerbation for prior 2 weeks ).

Exclusion criteria

Recent infective exacerbation in prior 2 weeks, pregnant/breastfeeding.

Outcome results