None listed
Conditions
Brief summary
In this trial we are testing the hypothesis that the addition of low dose heparin to total parenteral nutrition reduces the complications associated with long lines in neonates, particularly long line infections. We are investigating the possible benefits of heparin in improving the delivery of TPN to sick or premature neonates. In this study half of the babies will have heparin added to their TPN and the other half will have TPN without heparin. No one, except for the pharmacists, will know which babies are having heparin and which ones are not and this makes the trial double blind. At the end of the study we will compare the two groups to see if the babies that have had heparin have had less infections or less complications in general.
Interventions
Randomised double blind controlled trial with Heparin added to the total parenteral nutrition at a concentration of 0.5IU/mL. The intervention continues for as long as the infant is receiving total parenteral nutrition or a predetermined end site is reached, such as confirmed central line infection.
Sponsors
Dr Pita Birch
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
0 to 3 Years
Healthy volunteers
No
Inclusion criteria
All infants admitted to the Wellington Neonatal Unit requiring there first long line were eligible for inclusion.
Exclusion criteria
They were excluded if they had previously had an effective long line inserted and utilised. no other exclusion criteria.
Outcome results
None listed