A non-blinded randomised controlled study of the efficacy and safety of trimethoprim-sulfamethoxazole vs. norfloxacin for the prevention of spontaneous bacterial peritonitis in cirrhotic patients.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000560695

Enrollment

100

Registered

2005-09-30

Start date

2005-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Compare the safety and efficacy of trimethoprim-sulfamethoxazole and norfloxacin in preventing spontaneous bacterial peritonitis. Duration is 12 months.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Cirrhotic patient with ascites and either: 1) past history of spontaneous bacterial peritonitis, 2) ascitic protein concentration <15gm/L, 3) bilirubin >42micromol/L.

Exclusion criteria

No exclusion criteria

Outcome results