beta blockers and lung function in heart failure

Comparison of non-selective and beta1-selective beta-blockers on respiratory and arterial function and cardiac chamber dynamics in patients with chronic stable congestive cardiac failure

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000504617

Enrollment

Registered

2005-09-26

Start date

2005-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will compare 3 beta blocker tablets routinely used in treating patients with heart failure. There are theoretical reasons for differences between the tablets (particularly with respect to lung function and blood pressure changes), although this has not been tested in head-to-head comparison.

Interventions

Comparison of three clinically available beta-blockers (carvedilol, metoprolol succinate, bisoprolol) in cardiac failure.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Stable NYHA Class I, II, III CCF pts already receiving beta-blocker therapy. Half of study population to have defined (on basis of RFT testing) or treated airways disease.

Exclusion criteria

No exclusion criteria

Outcome results