A prospective double blind randomised clinical trial of 70% ethanol to treat proven or suspected catheter related sepsis in haematology patients.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000489695

Enrollment

Registered

2005-09-23

Start date

2002-04-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Routine antimircobials with the additon of daily 2 hourly locks of 70% ethanol. This intervention/control will continue until a clinical decision is made to stop the antimircobials.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Proven catheter related sepsis (same organism in both the peripheral blood and central line culture or from the FAS brush). Suspected CRS > 1000 organisms in either FAS sample or Central line blood culture. Consents to participate in the trial Haematological Malignancy Bone Marrow Transplantation.

Exclusion criteria

Known allergy to Ethanol Elevated LFTs (2.5 times above the upper normal range). Known history of Alcoholism. Pregnant of lactating women, Positive cultures both peripherally and centrally but NOT the same organism.

Outcome results