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Protein turnover and energy expenditure in normal subjects, growth hormone deficiency, acromegaly and Cushing's syndrome

Comparison of protein turnover and energy expenditure in growth hormone deficiency, acromegaly and Cushing's syndrome before and after surgery to normal subjects

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12605000445673
Enrollment
80
Registered
2005-09-21
Start date
1995-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Acromegaly, GH deficiency and Cushing's syndrome all alter body protein. The aim was to compare protein metabolism in these 3 conditions to normal subjects, along with how protein metabolism changes following surgical removal of hormone-secreting tumour.

Interventions

Resection of hormone secreting tumour in subjects with acromegaly and Cushing's syndrome only. the study involves observation of people who have undergone surgery as part of their routine medical care.

Sponsors

St Vincent's Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

Subjects with GH deficiency, acromegaly and Cushing's syndrome and normal volunteers.

Exclusion criteria

Cancer, hepatic and renal failure.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026