How is protein metabolism perturbed by long-term glucocorticoid use?

How is protein metabolism perturbed by long-term glucocorticoid use in subjects with polymyalgia rheumatica?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12605000444684

Enrollment

Registered

2005-09-21

Start date

2002-01-06

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Long-term glucocorticoid use causes substantial morbidity from protein loss. The aim was to determine how protein metabolism was perturbed in long-term glucocorticoid users.

Interventions

Nil

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Receiving long-term low dose glucocorticoids for PMR. No evidence of active inflammatory state.

Exclusion criteria

Diabetes, cancer, hepatic and renal failure.

Outcome results