Impact of short-term low dose glucocorticoids on protein metabolism

Impact of short-term low dose glucocorticoids on protein metabolism in normal subjects

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000443695

Enrollment

Registered

2005-09-21

Start date

2005-01-03

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to determine if short-term low dose glucocorticoids alters protein metabolism in a way that results in protein loss. This information will help in the development of therapies that reverse or prevent protein loss in patients requiring long-term glucocorticoids.

Interventions

Prednisolone 10mg/d for one week

Study design

Allocation

Non-randomised trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Healthy volunteers

Inclusion criteria

Healthy subjects.

Exclusion criteria

Diabetes mellitus, cancer, liver and kidney failure.

Outcome results