The effect of Glycine Betaine on fasting and Post methionine load homocysteine concentrations in healthy volunteers.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000434695

Enrollment

Registered

2005-09-16

Start date

2006-08-11

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

A 6-week intervention study investigating the effect of dietary manipulation versus dietary supplementation of glycine betaine on fasting and post-methionine load homocysteine concentrations.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Healthy volunteers with no previous history of vascular disease and no illness requiring medication, normal haemoglobin concentration.

Exclusion criteria

The presence of vitamin B12, vitamin B6 or folate deficiency, and/or 677C->T polymorphism in the methylene reductase gene.

Outcome results