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Dose-response to coenzyme Q10 supplementation with Q-Gel

Change in plasma coenzyme Q10 level after various doses of the coenzyme Q10 supplement Q-Gel in healthy volunteers

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12605000433606
Enrollment
18
Registered
2005-09-16
Start date
2005-11-09
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Four different treatments are to be used in this study. 1)single oral dose of 60 mg of coenzyme Q10 supplement Q-Gel (2 x 30 mg capsules); 2) single oral dose of 150 mg of coenzyme Q10 supplement Q-Gel (5 x 30 mg capsules); 3) single oral dose of 300 mg of coenzyme Q10 supplement Q-Gel (10 x 30 mg capsules); 4) single oral dose of 300 mg of coenzyme Q10 supplement Q-Gel (3 x 100 mg capsules). Each participant will receive all four treatments, one per week for four weeks. Treatments will be giv

Four different treatments are to be used in this study. 1)single oral dose of 60 mg of coenzyme Q10 supplement Q-Gel (2 x 30 mg capsules); 2) single oral dose of 150 mg of coenzyme Q10 supplement Q-Gel (5 x 30 mg capsules); 3) single oral dose of 300 mg of coenzyme Q10 supplement Q-Gel (10 x 30 mg capsules); 4) single oral dose of 300 mg of coenzyme Q10 supplement Q-Gel (3 x 100 mg capsules). Each participant will receive all four treatments, one per week for four weeks. Treatments will be given between 0800 and 0900 hours, after an overnight fast. For all doses, blood samples will be drawn at time 0, 2, 4, 6, 8, and 10 hours after the dose for the measurement of coenzyme Q10 in plasma. Lipid profiles (total cholesterol, LDL- and HDL-cholesterol and triglycerides) will also be measured on all samples.

Sponsors

Canterbury Health Laboratories
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
Male
Age
18 Years to 30 Years
Healthy volunteers
No

Inclusion criteria

Healthy.

Exclusion criteria

Smoker. Taking any supplements or prescription medication on a regular basis. Intercurrent illness.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026