Effect of exercise on mucus rheology and inspiratory/expiratory flow-volume relationships in people with Cystic Fibrosis

Effect of cycle and treadmill endurance exercise on mucus rheology and inspiratory/expiratory flow-volume relationships in people with Cystic Fibrosis

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000422628

Enrollment

Registered

2005-09-16

Start date

2005-05-25

Completion date

2007-07-06

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The trial completed recruitment and data collection in 2007. Manuscript was published in Chest 2011, vol 139(4):870-877.

Interventions

Stable subjects will attend for testing on three days. First day, lung function and incremental cycle and treadmill tests to peak work capacity (randomised order) will be performed. On the second and third day, subjects will be randomised to perform 20 minutes of endurance exercise at 60% of peak work capacity on the cycle ergometer and the treadmill.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Diagnosed with cystic fibrosis

Exclusion criteria

Post lung transplant; infected with burkholderia cepacia complex; not clinically stable

Outcome results