Effect of Positive Expiratory Pressure (PEP) Physiotherapy on the Duration of the Exacerbation-Free Period in People with Cystic Fibrosis (CF)

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000348651

Enrollment

Registered

2005-09-09

Start date

2003-09-26

Completion date

2004-09-25

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Positive expiratory pressure (PEP) physiotherapy (b.d.). For 24 weeks or until the first exacerbation.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Cystic fibrosis, stable clinical condition with an FEV1 within 15% of their best recorded value as an outpatient for the preceding six months and no non-routine antibiotic use within the preceding two weeks.

Exclusion criteria

FEV1 <30%pred, PaO2 <50mmHg, PaCO2 >55mmHg, or are listed for transplant. Subjects will be required to have had at least one exacerbation requiring hospital admission for antibiotic therapy within the past year.

Outcome results