None listed
Conditions
Brief summary
To determine if there is a better and safer option for pain relief following laparotomies for colorectal surgery, by using a continuous infusion of local anaesthetic into the wound.
Interventions
To determine whether continous local anaesthetic, ie. ropivacaine 1% (Naropin - produced by AstroZeneca) via a dual catheter PainBuster Soaker Pain Management System (produced by I-Flow) is a more effective form of post operative analgesia compared to traditional analgesias for midline incisions following major colorectal resections. The PainBuster Soaker System is tested in a randomised double blinded control study where participants either receive ropivacaine 1% or Saline in their PainBuster D
To determine whether continous local anaesthetic, ie. ropivacaine 1% (Naropin - produced by AstroZeneca) via a dual catheter PainBuster Soaker Pain Management System (produced by I-Flow) is a more effective form of post operative analgesia compared to traditional analgesias for midline incisions following major colorectal resections. The PainBuster Soaker System is tested in a randomised double blinded control study where participants either receive ropivacaine 1% or Saline in their PainBuster Device for the first three days. Both groups also receive a Morphine PCA, Tramadol, Ketorolac and Panadol.
Sponsors
Mazda Foundation - Private Bag 40, Mount Waverley BC, Vic 3149
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Undergoing open colorectal surgery (excluding abdomino-perineal resections) and that there is written informed consent.
Exclusion criteria
Allergies to lignocaine or ropivacaine, true allergy to morphine, epidural or intrathecal infusions, emergency surgery, and if the patient is mentally or legally incapacitated or if the have a prior history of altered mental state.
Outcome results
None listed