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Macrolide treatment of Non-Eosinophilic Asthma

A double blind randomised controlled study of the anti-inflammatory effects of clarithromycin 500mg twice daily for 8 weeks in adults with symptomatic Non-Eosinophilic Asthma

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12605000318684
Acronym
NEAT
Enrollment
64
Registered
2005-09-06
Start date
2004-07-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Clarithromycin 500mg twice daily for 8 weeks

Sponsors

Hunter New England Area Health Service
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

Symptomatic stable asthma, airway hyperresponsiveness and or bronchodilator response.

Exclusion criteria

Hypersensitivity to Macrolides, Other Respiratory Disease, Taking antihistamine medication, Pregnancy, Breast Feeding, Oral Corticosteroid use in past month, Antibiotic use in past month.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026