Quantifying the effect of nitrous oxide on the depth of anaesthesia using theoretically based time series modelling

The effect of nitrous oxide on a new measure of anaesthetic depth during sevoflurane anaesthesia

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000309684

Acronym

None

Enrollment

Registered

2005-09-06

Start date

2004-12-10

Completion date

2005-09-16

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to determine the effects of nitrous oxide on the EEG, by randomising patients to inhaled induction of anaesthesia using nitrous oxide 33% or 66% or 0% with sevoflurane

Interventions

Patient randomised to 0% (control), 33% or 66% nitrous oxide during induction of anaethesia with sevoflurane.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Diagnosis

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

Presenting for surgery, not at risk of gastrointestinal reflux during anaeshtesia, and without epilepsy or other EEG adnormalities.

Exclusion criteria

No exclusion criteria

Outcome results