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A randomised controlled trial of a brief self-help intervention for post infectious irritable bowel syndrome (IBS)

A randomised controlled trial of a brief self-help cognitive behavioural therapy intervention for symptom relief in post infectious irritable bowel syndrome (IBS)

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12605000286640
Enrollment
80
Registered
2005-09-05
Start date
2003-05-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Patients in this study were randomised to receive either a brief self-help intervention based on cognitive behavioural therapy (CBT) principles or standard medical care across the same seven week period. The self-help intervention developed specifically for this study consists of a structured manual divided into seven weekly sessions. The first chapter provides a detailed biopsychosocial model of IBS that explains why patients continue to experience symptoms after their initial infection and ju

Patients in this study were randomised to receive either a brief self-help intervention based on cognitive behavioural therapy (CBT) principles or standard medical care across the same seven week period. The self-help intervention developed specifically for this study consists of a structured manual divided into seven weekly sessions. The first chapter provides a detailed biopsychosocial model of IBS that explains why patients continue to experience symptoms after their initial infection and justifies the approach used in the manual. The remaining chapters provide behavioural guidelines for managing diarrhoea and constipation, advice on behavioural change for diet and exercise, cognitive strategies to challenge unhelpful thoughts or beliefs about symptoms, identifying and managing perfectionism, as well as stress and sleep management. Patients received the manual together with an initial face-to-face session with a CBT therapist explaining the programme and the model of IBS and two one-hour phone call follow-ups at 3 and 5 weeks into the programme with the same therapist.

Sponsors

Dr Rona Moss-Morris
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

(a) a diagnosis of IBS based on Rome I modified and/or Rome II criteria. (b) a diagnosis of IBS subsequent to an episode of gastroenteritis (c) between the ages of 18-70 (d) primary care attendees in the greater Auckland area.

Exclusion criteria

(a) Patients who have another medical condition that may affect their symptoms or preclude a diagnosis of IBS such as previous bowel surgery or a malignancy, ceoliac disease, inflammatory bowel disease, or obstructive bowel pathology (b) Patients who have any serious psychological disorders for whom treatment would be inappropriate including psychotic disorders or active substance abuse. (c). Non-English speakers and people who are unable to read and write English. (d) Should any participants alter their medication during this time period, or begin a course of anti-depressant medication their data will not be included in the final analysis. (e) Inclusion in another treatment trial.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026