A Randomised Controlled Trial of an Expert Weaning System (SmartcareTM) versus Usual Ventilatory Management in Critical Illness

Status

Not yet recruiting

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000265673

Enrollment

222

Registered

2005-09-02

Start date

2006-02-06

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Patients receiving mechanical ventilation for greater than 24 hours who meet the eligibility criteria will be randomised to receive weaning either by the usual care methods existing in the unit or via the SmartcareTM expert weaning system available on the Drager XL ventilators until they are ready for extubation.

Study design

Allocation

Randomised controlled trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Patient ventilated on non-spontaneous mode for 24 hoursPaO2/FiO2 > 150 or SaO2 90% with FiO2 .9PEEP 8cm H2OHemodynamically stable (Noradrenaline or Adrenaline less than 1 mg/hr)Body Temperature 36-39Â° CGlasgow coma score >4Stable neurological statusNo immediate requirements for transport or surgeryPass 30-minute pressure support testSmartcareTM enabled ventilator available for use.

Exclusion criteria

Patients with central nervous system disorders (e.g. stroke meningitis, cardiac arrest with neurologic sequelae) or neuromuscular disease (Guillain-Barre syndrome, myasthenia gravis).

Outcome results