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The ENERGII Trial

A randomised phase III study to evaluate the effects of a 6 week nutrition support and 12 week resistance exercise program in the treatment of nutritionally at risk older adults to improve nutritional status, function, quality of life and health care utilization.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12605000252617
Enrollment
200
Registered
2005-09-01
Start date
2000-09-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Oral nutritional supplement: 6 weeks of an individually prescribed supplement (6.3kJ/ml; 16% protein) administered via the medication cart by nursing staff on drug rounds. Thrice weekly visits for 6 weeks, weekly visits for 6 weeks. Lower extremity progressive resistance training intervention: 12 weeks individualized resistance training program supervised by a physiotherapist using resistive elastic bands. Combined nutritional supplement and resistance training intervention. Usual care in additi

Oral nutritional supplement: 6 weeks of an individually prescribed supplement (6.3kJ/ml; 16% protein) administered via the medication cart by nursing staff on drug rounds. Thrice weekly visits for 6 weeks, weekly visits for 6 weeks. Lower extremity progressive resistance training intervention: 12 weeks individualized resistance training program supervised by a physiotherapist using resistive elastic bands. Combined nutritional supplement and resistance training intervention. Usual care in addition to thrice weekly visits for 6 weeks and weekly visits for 6 weeks.

Sponsors

Professor Maria Crotty
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Factorial
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
70 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Resident of southern Adelaide SA, admitted for treatment of a fall-related lower limb fragility fracture, independent mobility prior to admission, permitted to full weight bear within 7 days of injury, medically stable, mid arm circumference <25th percentile of a large representative sample of older Australians.

Exclusion criteria

Difficulty comprehending simple commands, rapidly progressive or terminal illness, gastrectomy, malabsorption or dysphagia, medical condition where strength training or supplementary feeding may be hazardous.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026