The effect of heparin on lung function following cardiopulmonary bypass.

The effect of heparin on alveolar dead space following cardiopulmonary bypass.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000133639

Enrollment

Registered

2005-08-12

Start date

2004-11-30

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

A double blind randomised trial comparing intravenous heparin versus placebo (5% glucose). The infusion will be commenced 8 - 10 hours prior to commencement of surgery and ceased prior to the insertion of lines or sternotomy.

Study design

Allocation

Randomised controlled trial

Intervention model

Single group

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult patients undergong elective cardiac surgery for coronary artery bypass grafting with cardiopulmonary bypass.

Exclusion criteria

Previous adverse reaction to heparin. Active bleeding. An additional surgical procedure to coronary artery bypass grafting planned. Creatinine >200umol/L.

Outcome results