Botulinum toxin A and the neglected upper limb in children with hemiplegic cerebral palsy

The use of the assessment of motor and process skills (AMPS) in detecting a change in participation level function after botulinum toxin A injection in the upper limb of children with hemiplegic cerebral palsy

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000127606

Enrollment

Registered

2005-08-11

Start date

2004-06-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Botulinum toxin A (Botox) injection into the affected upper limb followed by 4 weeks of intensive occupational therapy (intervention)

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

3 Years to 16 Years

Healthy volunteers

Inclusion criteria

Children aged between 3-16 years of aged diagnosed with hemiplegic cerebral palsy, registered on the South Australian Cerebral Palsy register, elbow extension to neutral, wrist extension to 30 degrees past neutral with fingers extended, supination of forearm to 30 degrees past neutral, thumb extension to neutral, can initiate finger movements, tone on a modified Ashworth Scale >= 2/4 in at least one upper limb joint.

Exclusion criteria

Infection at the proposed injection site, Myasthenia Gravis, Eaton Lambert Syndrome, botulinum toxin A injection in a lower limb within the previous 6 months or upper limb within the previous 12 months.

Outcome results