A randomised phase II study of preoperative chemotherapy versus preoperative chemoradiation therapy for resectable carcinoma of the oesophagus and gastro-oesophageal junction

A randomised phase II study of feasability, toxicity and quality of life for patients undergoing preoperative chemotherapy versus preoperative chemoradiation therapy for resectable carcinoma of the oesophagus and gastro-oesophageal junction

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000108617

Enrollment

100

Registered

2005-08-09

Start date

2000-01-12

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Surgery, preoperative chemotherapy, preoperative chemoradiation therapy.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Histologically proven squamus cell carcinoma or adenocarcinoma of the oesophagus or gastro-oesophageal junction, resectable disease, no evidence of extrathoracic or extragastric spread apart from resectable perigastric or mediastinal nodes, adequate haematological & renal function, no previous radiation to the chest, no evidence of tracheo or broncho oesophageal fistula, written informed consent.

Exclusion criteria

No exclusion criteria

Outcome results