Activity, Diet and Blood Pressure Trial

A randomised phase III study to evaluate the effects of a lifestyle program in the treatment of hypertension to lower blood pressure and decrease antihypertensive drug needs.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000090617

Acronym

ADAPT

Enrollment

200

Registered

2005-08-05

Start date

2001-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Intervention and 1-year follow-up have been completed. Further 2-year follow-up is in progress.

Interventions

Behavioural program promoting weight loss, a low-sodium DASH-type diet, high in fish, increased physical activity & reduced alcohol intake with 4 months intervention and follow-up at 1 and 3 years after completion of the intervention.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

BMI>25 kg/m2, treated with one or two antihypertensive drugs for at least 3 months.

Exclusion criteria

Clinic BP > 160/90 mm Hg; consumption > 2 fish meals or 4 fish oil capsules per week; alcohol intake > 4 standard drinks/day for women and 6 standard drinks/day for men; drug- or insulin-treated diabetes; chronic renal failure (serum creatinine>120 umol/L); chronic liver disease; symptomatic cardiovascular disease < 3 months; other chronic debilitating disease; the use of antihypertensive drugs for indications other than hypertension, such as the use of beta blockers for arrhythmias

Outcome results