Does a 24% sucrose solution (used for procedural pain relief) have similar analgesic properties when given to infants of substance abusing mothers, compared to matched healthy infants

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12605000074695

Acronym

Does sucrose act differently i

Enrollment

Registered

2005-08-05

Start date

2005-07-02

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Sucrose when given to newborn infants has analgesic properties, especially when used for the relief of procedural pain. The calming effects of the sweet taste, cause the release of naturally occuring endorphins (morphine- like substances). The aim of this study is to show that sucrose has the same pain relieving effects in the infant of a substance dependent mother, compared to healthy (matched) infant.

Interventions

The aim of this study is to show that sucrose has a similar analgesic effect, when given to an infant born to a substance dependent mother, compared to a healthy matched infant. The secondary aim of this study is to objectively assess the effectiveness of sucrose with a modified pain assessment tool. Prospective cohort study. 26 healthy term infants (control) vs 26 Infants of substance abuse mothers. Compare the two groups response to a "heel stick" blood sample for the NSW Newborn Screening t

Eligibility

Sex/Gender

All

Age

37 Weeks to No maximum

Healthy volunteers

Inclusion criteria

Written infarmed consent for the NSW Newborn screening test as well as the research study. All infants must be greater than 37 weeks completed gestation.

Exclusion criteria

Symptoms of respiratory distress, problems with glucose metabolism, feed intolerance or necrotising entero-colitis, congenital anomalies, grade three or grade four intraventricular haemorrhages.

Outcome results