None listed
Conditions
Interventions
Ovarian stimulation with low dose rhFSH and randomised intrauterine insemination (IUI) or in vitro fertilisation (IVF).
Sponsors
Melbourne IVF
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1) Infertility of 12 months or longer duration2) Primary or secondary infertility3)New patient or patient returning after an interval of longer than 1 year4) Female age 18-42, male age 18-80 years5) Detailed male and female partner clinical evaluation, investigation of semen quality and objective evidence of ovulation and tubal patency
Exclusion criteria
1) Coital disorders, including infrequent or mistimed coitus (<1 per 3 days during mid cycle)2) Tubal obstruction (one or both) or known ligation.3) Male infertility requiring ICSI: average sperm concentration less than 2 million/mL, progressive motility less than 25%, or abnormal morphology greater than 85% in two or more semen test performed within the previous 12 month in RWH andrology lab, sperm autoimmunity (IBT IgG or IgA antibodies on >50% of motile sperm together with blocked sperm mucus penetration4) untreated ovulatory disorders5)Ovarian endometrioma6)Currently treated patients
Outcome results
None listed