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A comparison of two models of spirometry in general practice in the identification and prevention of COPD.

A cluster randomised crossover study comparing the efficacy of two models of spirometry provision in general practice on the identification and prevention of chronic obstructive pulmonary disease in smokers and ex-smokers over 35 years.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12605000019606
Acronym
MYLF STUDY
Enrollment
1500
Registered
2005-07-18
Start date
2004-11-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To increase recognition of airflow obstruction in primary care, two models of spirometry delivery in a target group at risk of chronic obstructive pulmonary disease (COPD) were compared in a qualitative/quantitative cluster randomised study in eight practices over 6 months; opportunistic spirometry by ‘‘visiting trained nurses’’ (TN) and optimised ‘‘usual care’’ (UC). In the eligible target population of smokers and ex-smokers aged over 35 years, 531/904 (59%) patients underwent spirometry in the TN model and 87/ 1130 (8%) patients in the UC model (p,0.0001). ATS spirometry standards for acceptability and reproducibility were met by 76% and 44% of tests in the TN and UC models, respectively (p,0.0001). GPs valued high quality spirometry and increased testing of patients at risk of COPD in the TN model. They identified limitations, including the need for better systematic follow-up of abnormal spirometry and support with interpretation, which may explain persisting underdiagnosis of COPD in practice records. Conclusions: Although opportunistic testing by visiting trained nurses substantially increased and improved spirometry performance compared with usual care, translating increased detection of airflow obstruction into diagnosis of COPD requires further support.

Interventions

1.Trained nurse provision of spirometry to people aged over 35 at risk of COPD in general practice using a portable electronic spirometer.

Sponsors

Dr Richard Wood-Baker
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
35 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Smokers and ex-smokers

Exclusion criteria

Unable to perform spirometry manoeuvres

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026