Bisphosphonate and Anastrozole trial - Bone Maintenance Algorithm Assessment

Maintaining skeletal health in postmenopausal women with surgically resected Stage I-IIIa hormone-receptor positive breast cancer who are receiving anastrozole, through the use of alendronate as determined by the Osteoporosis Australia Bone Maintenance Algorithm

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000003673

Acronym

BATMAN

Enrollment

300

Registered

2005-07-08

Start date

2005-07-05

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

This trial aims to assess the utility, through DEXA scans and biochemical markers of bone turnover, of a strategy of monitoring and intervention with oral alendronate in postmenopausal women with hormone-receptor positive breast cancer receiving five years of adjuvant anastrozole. It specifically addressed the issues of osteopaenic and osteoporotic women in this setting and will test three years versus five years of alendronate use.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Postmenopausal women- Adequately diagnosed and treated Stage I-IIIa early breast cancer- Oestrogen receptor and/or progesterone receptor positive breast cancer- Anastrozole is clinically indicated to be the best adjuvant strategy

Exclusion criteria

Clinical or radiological evidence of distant spread- prior treatment with bisphosphonates within the past 12 months

Outcome results