ZYTIGA 500 mg film-coated tablets
Sponsors
UZ Leuven, AstraZeneca AB, Bayer Consumer Care AG, Bayer AG, Aragon Pharmaceuticals Inc., Jiangsu Hengrui Pharmaceuticals Co. Ltd.
Conditions
Castration-Resistant Prostate CancerMetastatic Castration-Resistant Prostate CancerMetastatic Castration-Sensitive Prostate Cancer (mCSPC)Metastatic Prostate CancerOligoprogressive metastatic castration-refractory prostate cancerProstate Cancermetastatic castrate resistant prostate cancer (mCRPC)
Phase 1
Phase 3
Metastasis-directed therapy in oligoprogressive castration-refractory prostate cancer: a randomized phase 3 trial
RecruitingCTIS2022-502254-13-00
Start: 2023-12-18Target: 246Updated: 2025-07-18
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Study of ARN-509 in Men with Non-Metastatic (M0) Castration-Resistant Prostate Cancer
Active, not recruitingCTIS2023-509221-47-00
Start: 2014-02-12Target: 30Updated: 2025-12-09
A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of Saruparib (AZD5305) in Combination with Physician’s Choice New Hormonal Agents in Patients with HRRm and non-HRRm Metastatic Castration-Sensitive Prostate Cancer (EvoPAR-Prostate01).
RecruitingCTIS2023-504214-30-00
Start: 2024-06-27Target: 540Updated: 2025-11-13
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined with Abiraterone Acetate and Prednisone (AA-P) versus Placebo Combined with AA-P as First-Line Treatment in Patients with Metastatic Castration-Resistant Prostate Cancer
Active, not recruitingCTIS2023-509396-16-00
Start: 2021-11-08Target: 136Updated: 2025-12-05
A Randomised, Double-blind, Placebo-controlled, Phase III Study of Adjuvant Saruparib (AZD5305) in Patients with BRCAm Localised High-risk Prostate Cancer Receiving Radiotherapy with Androgen Deprivation Therapy (EvoPAR-Prostate02)
RecruitingCTIS2024-513586-39-00
Start: 2025-12-10Target: 253Updated: 2026-01-08