Zuranolone

DRUG4 trials

Sponsors

Biogen, Duke University

Conditions

Depression, PostpartumMajor Depressive DisorderPost Stroke DepressionPostpartum Depression

Phase 1

Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD)

CompletedNCT05655507

BiogenMajor Depressive Disorder

Start: 2023-04-19End: 2024-10-18Updated: 2025-03-26

Phase 2

Allopregnanolone (Zuranolone) in Post-stroke Depression

RecruitingNCT06759558

Duke UniversityPost Stroke Depression

Start: 2026-01-30End: 2027-06-30Target: 6Updated: 2026-09-03

Unknown Phase

A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy

CompletedNCT07047820

BiogenDepression, Postpartum

Start: 2025-06-30End: 2026-08-02Updated: 2026-09-08

A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone

RecruitingNCT07398469

BiogenPostpartum Depression

Start: 2025-12-22End: 2027-03-29Target: 300Updated: 2026-09-08