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Zongertinib

DRUG13 trials

Sponsors

Boehringer Ingelheim

Conditions

Colorectal CancerEsophageal AdenocarcinomaGastroesophageal Junction AdenocarcinomaHealthyLung Cancer, Non-squamous, Non-small CellMetastatic Breast CancerMetastatic Gastric AdenocarcinomaNeoplasm Metastasis

Phase 1

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
Active, not recruitingNCT04886804
Boehringer IngelheimNeoplasm Metastasis, Non-Small Cell Lung Cancer
Start: 2021-07-02End: 2028-08-30Target: 554Updated: 2026-08-20
A Study in Healthy Men to Test How Itraconazole Influences the Amount of Zongertinib (BI 1810631) in the Blood
CompletedNCT05833139
Boehringer IngelheimHealthy
Start: 2023-04-14End: 2023-06-12Updated: 2025-09-22
A Study in Healthy Men to Test How Zongertinib (BI 1810631) is Taken up and Processed by the Body
CompletedNCT05879991
Boehringer IngelheimHealthy
Start: 2023-08-10End: 2023-10-19Updated: 2025-10-06
A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Zongertinib in the Blood
CompletedNCT06028464
Boehringer IngelheimHealthy
Start: 2023-09-11End: 2023-12-08Updated: 2025-11-05
A Study in Healthy Men to Test How Zongertinib is Taken up in the Body When Taken With or Without Food
CompletedNCT06075277
Boehringer IngelheimHealthy
Start: 2023-10-19End: 2024-01-02Updated: 2025-09-22
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
RecruitingNCT06324357
Boehringer IngelheimColorectal Cancer, Esophageal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma +2
Start: 2024-06-28End: 2029-01-08Target: 768Updated: 2026-09-16
A Study in Healthy Men to Test Whether Zongertinib Affects How 3 Other Medicines (Midazolam, Omeprazole, and Repaglinide) Are Taken up and Processed by the Body
CompletedNCT06494761
Boehringer IngelheimHealthy
Start: 2024-07-30End: 2024-10-16Updated: 2025-12-02
A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood
CompletedNCT06504862
Boehringer IngelheimHealthy
Start: 2024-08-20End: 2024-12-18Updated: 2026-01-09
A Study in Healthy Men to Test How Bosentan Influences the Amount of Zongertinib in the Blood
CompletedNCT07649941
Boehringer IngelheimHealthy
Start: 2026-06-22End: 2026-08-24Updated: 2026-09-04

Phase 2

Phase 3

Related Papers

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