Zinlirvimab

DRUG2 trials

Sponsors

Gilead Sciences

Conditions

HIV InfectionHIV-1 Infection

Phase 1

Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection

CompletedNCT04811040

Gilead SciencesHIV-1 Infection

Start: 2021-04-08End: 2023-10-26Updated: 2025-01-27

Phase 2

A Study of Teropavimab and Zinlirvimab in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection

Active, not recruitingNCT05729568

Gilead SciencesHIV Infection

Start: 2023-05-15End: 2029-12-31Updated: 2025-07-15

Related Papers

Resistance Analysis of Low-Level Virologic Rebound During HIV-1 Treatment With Lenacapavir and Broadly Neutralizing Antibodies Teropavimab and Zinlirvimab.

2026-01-01

P-1248. Phase 2 Pharmacokinetics and Anti-Drug Antibody Results of the Investigational Twice-Yearly HIV-1 Treatment Regimen Lenacapavir, Teropavimab, and Zinlirvimab

Open Forum Infectious Diseases2026-01-01

P-365. Pooled safety and tolerability of twice-yearly lenacapavir with teropavimab and zinlirvimab for HIV-1 treatment

Open Forum Infectious Diseases2026-01-01

Lenacapavir Plus 2 Broadly Neutralizing Antibodies, Teropavimab and Zinlirvimab, for People With HIV-1 Highly Susceptible to Either Teropavimab or Zinlirvimab

The Journal of Infectious Diseases2025-03-304 citations

Safety of teropavimab and zinlirvimab with lenacapavir once every 6 months for HIV treatment: a phase 1b, randomised, proof-of-concept study.

2024-01-3031 citations