ZIMINO 2

DRUG3 trials

Sponsors

CHRU De Nancy, Assistance Publique Hopitaux De Paris

Conditions

Cardiogenic ShockPatients referred for an isolated or a combined surgical correction of functional moderate to severe tricuspid regurgitationsubarachnoid hemorrhages of aneurysmal origin (HSAa)

Phase 2

LEVOSAH - Pilot study comparing the effectiveness of adding treatment with Levosimendan to usual care for the management of the acute phase of aneurysmal subarachnoid hemorrhages

Not yet recruitingCTIS2024-514242-36-00

Assistance Publique Hopitaux De Parissubarachnoid hemorrhages of aneurysmal origin (HSAa)

Target: 30Updated: 2025-09-16

Phase 3

Effect of early use of levosimendan versus placebo on top of a conventional strategy of inotrope use on a combined morbidity-mortality endpoint in patients with cardiogenic shock. LevoHeartShock

RecruitingCTIS2024-513811-29-00

CHRU De NancyCardiogenic Shock

Start: 2023-07-03Target: 610Updated: 2025-07-30

LEONARD.LEvOsimendaN vs. Placebo Before Tricuspid VAlve Surgery in Patients with Right Ventricular Dysfunction (LEONARD)

Not yet recruitingCTIS2024-516167-86-00

Assistance Publique Hopitaux De ParisPatients referred for an isolated or a combined surgical correction of functional moderate to severe tricuspid regurgitation

Target: 230Updated: 2025-08-22