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Zelvina 5 mg hard capsules

DRUG10 trials

Sponsors

Incyte Corp., Sanofi-Aventis Recherche & Developpement, Incyte Corp., Incyte Corp., Pfizer Inc., Glaxosmithkline Research & Development Limited

Conditions

CancerDiffuse large B-cell lymphoma (DLBCL)Multiple MyelomaMultiple myelomaPlasma cell myelomaRelapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)follicular lymphoma (FL) and marginal zone lymphoma (MZL)

Phase 1

Phase 2

Phase 3

A Phase 3, Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Active, not recruitingCTIS2023-505579-53-00
Incyte Corp.Diffuse large B-cell lymphoma (DLBCL)
Start: 2022-10-25Target: 74Updated: 2025-07-24
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Tafasitamab Plus Lenalidomide in Addition to Rituximab Versus Lenalidomide in Addition to Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma Grade 1 to 3a or R/R Marginal Zone Lymphoma
Active, not recruitingCTIS2023-504684-16-00
Incyte Corp.follicular lymphoma (FL) and marginal zone lymphoma (MZL)
Start: 2021-06-05Target: 345Updated: 2025-10-02
A Phase 3 randomized, open-label, multicenter study of isatuximab (SAR650984) in combination with lenalidomide and dexamethasone versus lenalidomide and dexamethasone in patients with high-risk smoldering multiple myeloma
Active, not recruitingCTIS2023-507419-37-00
Sanofi-Aventis Recherche & DeveloppementPlasma cell myeloma
Start: 2020-06-25Target: 272Updated: 2025-10-06
C1071007 - MAGNETISMM-7 A RANDOMIZED, 2-ARM, PHASE 3 STUDY OF ELRANATAMAB (PF-06863135) VERSUS LENALIDOMIDE IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA AFTER UNDERGOING AUTOLOGOUS STEM-CELL TRANSPLANTATION
Active, not recruitingCTIS2023-508897-27-00
Pfizer Inc.Multiple Myeloma
Start: 2022-04-28Target: 377Updated: 2025-11-27
C1071006 – An Open-Label, 2-Arm, Multicenter, Randomized Phase 3 Study To Evaluate The Efficacy And Safety of Elranatamab (PF-06863135) + Daratumumab + Lenalidomide Versus Daratumumab + Lenalidomide + Dexamethasone in Transplant-Ineligible or Transplant-Deferred Participants With Newly Diagnosed Multiple Myeloma
RecruitingCTIS2024-514139-50-00
Pfizer Inc.Multiple myeloma
Start: 2022-11-14Target: 558Updated: 2025-12-04
A Phase 3 Randomized, Open-label, Multicenter Study Assessing the Clinical Benefit of Isatuximab (SAR650984) in Combination with Bortezomib (Velcade®), Lenalidomide and Dexamethasone versus Bortezomib, Lenalidomide and Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
Active, not recruitingCTIS2024-514417-34-00
Sanofi-Aventis Recherche & DeveloppementCancer
Start: 2017-12-14Target: 308Updated: 2025-05-12
A Phase 3, randomized, open-label study of belantamab mafodotin administered in combination with lenalidomide and dexamethasone versus daratumumab, lenalidomide, and dexamethasone in participants with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation (TI-NDMM)-DREAMM-10
RecruitingCTIS2024-516030-35-00
Glaxosmithkline Research & Development LimitedMultiple myeloma
Start: 2025-04-30Target: 225Updated: 2025-10-16