Zelvina 10 mg hard capsules
Sponsors
Incyte Corp., Sanofi-Aventis Recherche & Developpement, Incyte Corp., Incyte Corp., Pfizer Inc., Glaxosmithkline Research & Development Limited
Conditions
CancerDiffuse large B-cell lymphoma (DLBCL)Multiple MyelomaMultiple myelomaPlasma cell myelomaRelapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)follicular lymphoma (FL) and marginal zone lymphoma (MZL)
Phase 1
A Phase 1b/2, Open-Label, Multicenter Study to Evaluate the Safety and Pharmacokinetics of a Modified Tafasitamab IV Dosing Regimen Combined with Lenalidomide (LEN) in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL) (MINDway)
Active, not recruitingCTIS2023-507993-42-00
Start: 2022-03-17Target: 38Updated: 2025-07-07
A Phase I/II, Randomized, Open-label Platform Study Utilizing a Master Protocol to Study Belantamab Mafodotin (GSK2857916) as Monotherapy and in Combination with Anti-Cancer Treatments in Participants with Relapsed/Refractory Multiple Myeloma (RRMM)–DREAMM5.
Active, not recruitingCTIS2023-509550-55-00
Start: 2020-01-21Target: 62Updated: 2025-10-10
Phase 2
Phase 3
A Phase 3, Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Active, not recruitingCTIS2023-505579-53-00
Start: 2022-10-25Target: 74Updated: 2025-07-24
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Tafasitamab Plus Lenalidomide in Addition to Rituximab Versus Lenalidomide in Addition to Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma Grade 1 to 3a or R/R Marginal Zone Lymphoma
Active, not recruitingCTIS2023-504684-16-00
Start: 2021-06-05Target: 345Updated: 2025-10-02
A Phase 3 randomized, open-label, multicenter study of isatuximab (SAR650984) in combination with lenalidomide and dexamethasone versus lenalidomide and dexamethasone in patients with high-risk smoldering multiple myeloma
Active, not recruitingCTIS2023-507419-37-00
Start: 2020-06-25Target: 272Updated: 2025-10-06
C1071007 - MAGNETISMM-7
A RANDOMIZED, 2-ARM, PHASE 3 STUDY OF ELRANATAMAB (PF-06863135) VERSUS LENALIDOMIDE IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA AFTER UNDERGOING AUTOLOGOUS STEM-CELL TRANSPLANTATION
Active, not recruitingCTIS2023-508897-27-00
Start: 2022-04-28Target: 377Updated: 2025-11-27
C1071006 – An Open-Label, 2-Arm, Multicenter, Randomized Phase 3 Study To Evaluate The Efficacy And Safety of Elranatamab (PF-06863135) + Daratumumab + Lenalidomide Versus Daratumumab + Lenalidomide + Dexamethasone in Transplant-Ineligible or Transplant-Deferred Participants With Newly Diagnosed Multiple Myeloma
RecruitingCTIS2024-514139-50-00
Start: 2022-11-14Target: 558Updated: 2025-12-04
A Phase 3 Randomized, Open-label, Multicenter Study Assessing the Clinical Benefit of Isatuximab (SAR650984) in Combination with Bortezomib (Velcade®), Lenalidomide and Dexamethasone versus Bortezomib, Lenalidomide and Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
Active, not recruitingCTIS2024-514417-34-00
Start: 2017-12-14Target: 308Updated: 2025-05-12
A Phase 3, randomized, open-label study of belantamab mafodotin administered in combination with lenalidomide and dexamethasone versus daratumumab, lenalidomide, and dexamethasone in participants with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation (TI-NDMM)-DREAMM-10
RecruitingCTIS2024-516030-35-00
Start: 2025-04-30Target: 225Updated: 2025-10-16