Zanamivir

DRUG12 trials

Sponsors

Mount Sinai Hospital, Canada, National Institute of Allergy and Infectious Diseases (NIAID), Chinese University of Hong Kong, GlaxoSmithKline, Jiangsu Simcere Pharmaceutical Co., Ltd.

Conditions

ArthralgiaDengue FeverDiabetes Mellitus, Type 2InfluenzaInfluenza A Virus InfectionInfluenza A Virus, H1N1 SubtypeInfluenza B Virus InfectionInfluenza, Human

Phase 1

Pharmacokinetic Study of Oseltamivir and Intravenous Zanamivir in Healthy Adults

CompletedNCT00921726

National Institute of Allergy and Infectious Diseases (NIAID)Influenza, Virus Diseases

Start: 2009-07-31End: 2009-10-31Updated: 2010-03-19

Crossover Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Repeat Dose Zanamivir/Placebo Via Devices Administered Twice Daily for 5 Days

CompletedNCT00989404

GlaxoSmithKlineInfluenza A Virus, H1N1 Subtype

Start: 2009-10-12End: 2009-12-07Updated: 2017-06-14

Pharmacokinetics of Zanamivir After Single and Repeated Dose Infusion Administration in Healthy Chinese Adults

CompletedNCT02377401

GlaxoSmithKlineInfluenza, Human

Start: 2015-04-28End: 2015-06-19Updated: 2017-05-09

Phase 2

An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection

RecruitingNCT04494412

GlaxoSmithKlineArthralgia, Influenza, Human

Start: 2022-11-21End: 2026-04-30Target: 12Updated: 2025-03-17

Zanamivir Treatment of Vascular Permeability in Dengue (ZAP-DENGUE)

RecruitingNCT04597437

George Washington UniversityDengue Fever

Start: 2024-03-15End: 2026-09-30Target: 74Updated: 2025-07-28

Role of Neuraminidase Activity on Endothelial Dysfunction in Type 2 Diabetes

CompletedNCT04867707

University of Missouri-ColumbiaDiabetes Mellitus, Type 2

Start: 2021-07-14End: 2024-10-18Updated: 2025-04-25

A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza

RecruitingNCT05648448

University of OxfordInfluenza, Influenza, Human

Start: 2023-02-22End: 2027-01-01Target: 3000Updated: 2026-02-19

Phase 3

Zanamivir Versus Trivalent Split Virus Influenza Vaccine

CompletedNCT00784784

Mount Sinai Hospital, CanadaInfluenza

Start: 2008-11-30End: 2009-06-30Updated: 2014-11-21

A Clinical Trial Comparing Oseltamivir With Placebo And Zanamivir With Control As First Line Treatment For Human Swine Influenza Infection

TerminatedNCT00979667

Chinese University of Hong KongInfluenza, Upper Respiratory Tract Infection

Start: 2009-10-31End: 2010-10-31Updated: 2011-04-11

A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza

CompletedNCT01231620

GlaxoSmithKlineInfluenza, Human

Start: 2011-01-15End: 2015-03-18Updated: 2018-10-15

Efficacy and Safety of Inhaled Zanamivir in Treatment of Influenza A and B Virus Infections in China

CompletedNCT01459081

Jiangsu Simcere Pharmaceutical Co., Ltd.Influenza A Virus Infection, Influenza B Virus Infection

Start: 2011-10-31End: 2012-12-31Updated: 2013-01-16

Unknown Phase

Relenza® Sentinel Site Monitoring Program in Japan

CompletedNCT01199744

GlaxoSmithKlineInfluenza, Human

Start: 2009-11-30End: 2010-04-30Updated: 2017-07-06

Related Papers

Neuraminidase inhibition improves endothelial function in diabetic mice.

2023-10-067 citations

The Hospital Recovery Scale: A clinically useful endpoint in patients hospitalized with influenza.

2022-10-035 citations

Intravenous zanamivir or oral oseltamivir for hospitalised patients with influenza: an international, randomised, double-blind, double-dummy, phase 3 trial.

2017-01-1472 citations

Safety and Pharmacokinetics of Intravenous Zanamivir Treatment in Hospitalized Adults With Influenza: An Open-label, Multicenter, Single-Arm, Phase II Study

The Journal of Infectious Diseases2013-08-2754 citations