zagociguat 15mg

DRUG2 trials

Sponsors

Tisento Therapeutics

Conditions

Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

Phase 2

A Phase 2b Study of Zagociguat in Patients With MELAS

CompletedNCT06402123

Tisento TherapeuticsMitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

Start: 2024-09-10End: 2026-06-29Updated: 2026-07-07

An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

Active, not recruitingNCT06961344

Tisento TherapeuticsMitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

Start: 2025-08-18End: 2028-07-01Target: 44Updated: 2026-07-07