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yttrium-90 radioembolization

RADIATION6 trials

Sponsors

University of Hawaii, Case Comprehensive Cancer Center, University of Iowa, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Brown University

Conditions

Colo-rectal CancerColon CancerColorectal AdenocarcinomaColorectal Cancer MetastaticColorectal CarcinomaColorectal Carcinoma Metastatic in the LiverColorectal NeoplasmsHepatocellular Cancer

Phase 1

Sorafenib Concurrent With Yttrium-90 Transarterial Radioembolization in Patients With Advanced Hepatocellular Cancer
WithdrawnNCT02288507
University of HawaiiHepatocellular Cancer
Start: 2014-11-30End: 2016-08-31Updated: 2019-11-08
Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer
WithdrawnNCT03307603
Case Comprehensive Cancer CenterMetastatic Colorectal Cancer
Start: 2018-12-31End: 2021-03-31Updated: 2018-02-27
Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer
TerminatedNCT04108481
University of IowaColon Cancer, Colorectal Adenocarcinoma, Colo-rectal Cancer +7
Start: 2020-10-05End: 2023-11-17Updated: 2025-03-28

Phase 2

Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC
RecruitingNCT06555133
Brown UniversityColorectal Carcinoma Metastatic in the Liver
Start: 2025-04-07End: 2029-09-01Target: 18Updated: 2026-08-20
Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT)
RecruitingNCT07312292
Niek WijnenLiver Cancer Adult, Liver Cancer (Locally Advanced or Metastatic)
Start: 2026-01-01End: 2027-11-01Target: 15Updated: 2026-03-30

Unknown Phase

Radioembolization for Hepatocellular Carcinoma With Portal Vein Tumoral Thrombosis
CompletedNCT04771988
IRCCS Azienda Ospedaliero-Universitaria di BolognaHepatocellular Carcinoma
Start: 2013-05-08End: 2020-12-31Updated: 2021-02-25

Related Papers

METEORITE: A phase II study of Y-90, capecitabine, and atezolizumab in oligometastatic CRC (BrUOG430).
Journal of Clinical Oncology2026-01-10
331 Immunotherapy with Y90-radioembolization for metastatic colorectal cancer (iRE-C)
Regular and Young Investigator Award Abstracts2020-11-01
Immunotherapy with Y90-radioembolization for metastatic colorectal cancer (iRE-C).
Journal of Clinical Oncology2020-02-013 citations