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YK012

DRUG6 trials

Sponsors

Excyte Biopharma Ltd, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Conditions

B-cell Acute Lymphoblastic LeukemiaPrimary Membranous NephropathyRelapsed or Refractory B-Cell Non-Hodgkin LymphomaSystem Lupus Erythematosus(SLE)Systemic Lupus Erythematosus (SLE)

Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of YK012
RecruitingNCT06565689
Excyte Biopharma LtdRelapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Start: 2023-05-09End: 2028-12-01Target: 48Updated: 2026-07-17
Study of YK012 in B-cell Acute Lymphoblastic Leukemia
RecruitingNCT06580301
Excyte Biopharma LtdB-cell Acute Lymphoblastic Leukemia
Start: 2024-09-25End: 2027-06-30Target: 46Updated: 2026-02-06
Study of YK012 in Primary Membranous Nephropathy
RecruitingNCT06982729
Excyte Biopharma LtdPrimary Membranous Nephropathy
Start: 2025-03-08End: 2027-12-31Target: 72Updated: 2025-11-17
Study of YK012 in Moderate to Severe Systemic Lupus Erythematosus
RecruitingNCT07010835
Excyte Biopharma LtdSystemic Lupus Erythematosus (SLE)
Start: 2025-08-25End: 2028-12-01Target: 189Updated: 2026-02-05
A Phase I Study of YK012 in Primary Membranous Nephropathy
Not yet recruitingNCT07234474
Excyte Biopharma LtdPrimary Membranous Nephropathy
Start: 2026-10-01End: 2028-02-01Target: 66Updated: 2026-02-05
Study of YKST02 Alone or in Combination With YK012 in Patients With Active or Refractory Systemic Lupus Erythematosus
Not yet recruitingNCT07512947
Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologySystem Lupus Erythematosus(SLE)
Start: 2026-05-01End: 2028-06-30Target: 30Updated: 2026-04-06