Xeloda 500 mg film-coated tablets
Sponsors
Unicancer, Gilead Sciences Inc., Grupo Espanol De Investigacion En Cancer De Mama, Glaxosmithkline Research & Development Limited, Amsterdam UMC
Conditions
Breast CancerHER2-negative breast cancerHER2-negative breast cancer patients with high relapse risk after
standard neoadjuvant treatmentLocally advanced or metastatic hormone receptor (HR)-positiveMetastatic colorectal cancerParticipants with Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon CancerPatients having a HER2-amplified metastatic breast cancer with evolutive leptomeningeal metastases (LM) requiring intrathecal therapyPatients with invasive breast cancer in early stages
Phase 1
Phase 2
ETIC-LM_Multicentric single arm phase II study evaluating the Efficacy of association of Tucatinib, capecitabine and Intra-CSF trastuzumab in HER2 amplified breast cancer patients with Leptomeningeal Metastases.
RecruitingCTIS2022-502351-60-00
Start: 2024-02-22Target: 30Updated: 2025-04-17
Liposomal iRInotecan, Carboplatin or oXaliplatin in the first line treatment of esophagogastric cancer: a randomized phase 2 study (LyRICX)
Active, not recruitingCTIS2023-509287-26-00
Start: 2019-07-01Target: 322Updated: 2025-11-04
Neoadjuvant capecitabine, oxaliplatin, docetaxel and atezolizumab in non-metastatic, resectable gastric and GE-junction cancer - de PANDA trial
RecruitingCTIS2024-519075-26-00
Start: 2018-02-27Target: 21Updated: 2024-11-21
REPROGRAM-02 : Induction Regorafenib in combination with metronomic cyclophosphamide, capecitabine, and low-dose aspirin followed by chemotherapy in second line metastatic colorectal cancer carcinoma
An open-label randomized phase II-III study
Not yet recruitingCTIS2024-516709-22-00
Target: 94Updated: 2025-10-08
Master Protocol: A Phase 1b / 2, Multicenter, Multi Arm Study of Evorpacept in Combination with Anti-cancer Therapies in Advanced / Metastatic Malignancies (ASPEN-09)
Substudy Protocol: A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination with Trastuzumab and Chemotherapy in Participants with Metastatic HER2-Positive Breast Cancer (ASPEN-09-03)
Not yet recruitingCTIS2025-522012-16-00
Target: 36Updated: 2026-01-23
An Open-label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Induction Treatment with Melphalan/HDS Followed by Consolidation Treatment with Eribulin or Vinorelbine or Capecitabine Versus Eribulin or Vinorelbine or Capecitabine Alone in Patients with Metastatic Breast Cancer with Liver Dominant Disease
Not yet recruitingCTIS2025-521966-91-00
Target: 3Updated: 2026-02-04
Phase 3
A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Patients With Hormone Receptor-Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2−) (HER2 IHC0 or HER2-low [IHC 1+, IHC 2+/ISH−]) Inoperable, Locally Advanced, or Metastatic Breast Cancer and Have Received Endocrine Therapy
Active, not recruitingCTIS2022-502593-17-00
Start: 2023-09-19Target: 428Updated: 2025-11-24
A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy versus Standard of Care in Participants with Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Active, not recruitingCTIS2023-503265-27-00
Start: 2023-11-23Target: 477Updated: 2025-10-20
CARE : Impact of Regorafenib in combination with multimodal metronomic chemotherapy (cyclophosphamide, capecitabine, and low-dose aspirin) on progression-free survival compared with standard Regorafenib for the treatment of chemo-resistant metastatic colorectal cancers
RecruitingCTIS2023-509761-21-00
Start: 2024-07-08Target: 174Updated: 2024-08-28
Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant treatment - SASCIA
Active, not recruitingCTIS2023-510390-33-00
Start: 2020-10-23Target: 1386Updated: 2025-12-18
Short course radiotherapy versus chemoradiotherapy, followed by consolidation chemotherapy, and selective organ preservation for MRI-defined intermediate and high-risk rectal cancer patients, A randomized phase III trial of the German Rectal Cancer Study Group
Active, not recruitingCTIS2024-511577-29-01
Start: 2020-03-13Target: 688Updated: 2026-01-26
An open-label, randomised, phase III study comparing trifluridine/tipiracil (S 95005) in combination with bevacizumab to capecitabine in combination with bevacizumab in first-line treatment of patients with metastatic colorectal cancer who are not candidate for intensive therapy (SOLSTICE study).
RecruitingCTIS2024-516180-85-00
Start: 2019-04-15Target: 84Updated: 2025-09-29
A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician’s Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy
RecruitingCTIS2024-512279-10-00
Start: 2024-11-25Target: 758Updated: 2026-01-26
BALLAD Belgium - A trial to evaluate the potential benefit of adjuvant chemotherapy for small bowel adenocarcinoma. The Belgian component of the Global Ballad pooled data analysis.
Not yet recruitingCTIS2024-518349-85-01
Target: 30Updated: 2024-11-20