Wide Local Excision

PROCEDURE5 trials

Sponsors

University of Kansas Medical Center, Mayo Clinic, Wake Forest University Health Sciences, Eastern Cooperative Oncology Group, Children's Oncology Group

Conditions

Clinical Stage 0 Cutaneous Melanoma AJCC v8Clinical Stage I Cutaneous Melanoma AJCC v8Clinical Stage II Cutaneous Melanoma AJCC v8Cutaneous Melanocytic NeoplasmCutaneous MelanomaCutaneous Spitz MelanocytomaCutaneous Spitz MelanomaDermatofibrosarcoma Protuberans

Phase 3

A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

Not yet recruitingNCT07068074

Eastern Cooperative Oncology GroupCutaneous Melanoma

Start: 2025-12-12End: 2031-01-01Target: 428Updated: 2025-11-13

Unknown Phase

Study of 1cm Versus 2cm Margins for the Surgical Treatment of cT2N0M0 Melanoma

CompletedNCT03034395

University of Kansas Medical CenterMalignant Melanoma

Start: 2017-01-30End: 2020-11-04Updated: 2021-05-03

Treatment of Dermatofibrosarcoma Protuberans in Patients 10 Years and Younger

CompletedNCT03381846

Mayo ClinicDermatofibrosarcoma Protuberans

Start: 2018-07-01End: 2020-06-30Updated: 2020-08-05

A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia

Active, not recruitingNCT05934851

Wake Forest University Health SciencesDysplasia Vulvar, Vulvar Neoplasm

Start: 2023-11-07End: 2026-10-24Target: 112Updated: 2026-07-13

A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

RecruitingNCT07621614

Children's Oncology GroupClinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8, Clinical Stage II Cutaneous Melanoma AJCC v8 +4

Start: 2027-05-15End: 2028-07-31Target: 51Updated: 2026-09-02

Related Papers

A prospective, randomized, single-blinded study evaluating the effect of frozen-section directed excision on positive surgical margins in high-grade vulvar dysplasia.

Journal of Clinical Oncology2024-06-01