whole-brain radiation therapy

RADIATION8 trials

Conditions

Cognitive/Functional EffectsLeukemiaLung CancerMale Breast CancerMetastatic CancerNeurotoxicityRadiation ToxicityStage IV Breast Cancer

Phase 1

Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer

TerminatedNCT00892801

Vanderbilt-Ingram Cancer CenterLung Cancer, Metastatic Cancer

Start: 2009-05-31End: 2011-02-28Updated: 2012-03-12

Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer

TerminatedNCT00937482

National Cancer Institute (NCI)Male Breast Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer +7

Start: 2009-08-31Updated: 2013-03-08

Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

TerminatedNCT01018836

Rutgers, The State University of New JerseyMetastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific

Start: 2009-11-30End: 2013-12-31Updated: 2014-05-02

Phase 2

Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL

CompletedNCT01228331

Universitätsklinikum Hamburg-EppendorfLeukemia

Start: 2010-10-31End: 2024-11-20Updated: 2024-12-11

Phase 3

Radiation Therapy to the Brain or Observation in Preventing Brain Metastases in Patients With Advanced Non-Small Cell Lung Cancer

NCT00955695

National Cancer Center, KoreaLung Cancer

Start: 2009-05-31Target: 242Updated: 2013-08-02

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

CompletedNCT01372774

Alliance for Clinical Trials in OncologyCognitive/Functional Effects, Metastatic Cancer, Neurotoxicity +2

Start: 2011-07-31End: 2019-12-15Updated: 2022-09-16

Unknown Phase

Palliative 3-Dimensional Conformal Radiation Therapy in Reducing Radiation Side Effects in Patients With Lung Cancer. ICORG 06-34

CompletedNCT01176487

Cancer Trials IrelandLung Cancer

Start: 2010-06-30End: 2016-03-31Target: 40Updated: 2016-03-31

Voxel Based Diffusion Tensor Imaging in Predicting Response in Patients With Brain Metastases Undergoing Whole Brain Radiation Therapy or Stereotactic Radiosurgery

WithdrawnNCT02277561

Albert Einstein College of MedicineTumors Metastatic to Brain, Unspecified Adult Solid Tumor, Protocol Specific

Start: 2013-04-30End: 2014-12-31Updated: 2020-03-04

Neuro-Oncology2022-12-0615 citations

Association of Long-term Outcomes With Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Brain Metastasis

JAMA Oncology2022-10-2062 citations

Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group.

PubMed2022-05-014 citations

Examiner accuracy in cognitive testing in multisite brain-tumor clinical trials: an analysis from the Alliance for Clinical Trials in Oncology

Neuro-Oncology Practice2018-11-244 citations

Cancer Trials Ireland (ICORG) 06-34: A multi-centre clinical trial using three-dimensional conformal radiation therapy to reduce the toxicity of palliative radiation for lung cancer.

2018-03-1315 citations

Post-Resection Stereotactic Radiosurgery in the Treatment of Brain Metastases

Oncology Times2018-02-09

NCOG-06. N107C/CEC.3 (ALLIANCE FOR CLINICAL TRIALS IN ONCOLOGY/CANADIAN CANCER TRIALS GROUP): PHASE III TRIAL OF POST-OPERATIVE RADIOSURGERY COMPARED WITH WHOLE BRAIN RADIOTHERAPY FOR RESECTED METASTATIC BRAIN DISEASE: COGNITIVE FUNCTION OF LONG-TERM SURVIVORS

Neuro-Oncology2017-11-01

Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial.

2017-07-04825 citations