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Wegovy 0.5 mg FlexTouch solution for injection in pre-filled pen

DRUG9 trials

Sponsors

Novo Nordisk A/S, Trinity College Dublin, Clinical Pharmacology, Department of, Kailera Therapeutics Inc., Karolinska University Hospital

Conditions

AdipositasAdult subjects with HIV infection on stable antiretroviral therapy.Arterial hypertensionAtrial fibrillationCardiovascular disorders: Hypertension and ObesityDyslipidaemiaObesityObesity and overweight

Phase 2

Semaglutide for the treatment of visceral obesity in people with HIV with body mass index <30 kg/m2 and without diabetes: a randomized clinical trial to explore immune metabolism, systemic and vascular inflammation assessed with Positron Emission Tomography
Not yet recruitingCTIS2026-526738-18-00
Azienda Ospedaliero Universitaria Di ModenaAdult subjects with HIV infection on stable antiretroviral therapy.
Target: 66Updated: 2026-10-12

Phase 3

Long-term safety and efficacy of semaglutide s.c. once-weekly on weight management in children and adolescents (aged 6 to <18 years) with obesity or overweight
Active, not recruitingCTIS2022-502922-41-00
Novo Nordisk A/SObesity and overweight
Start: 2023-07-03Target: 86Updated: 2025-11-03
Semaglutide for people with obesity and resistant hypertension (SUPPORT): a pilot, randomized, parallel-group, integrated, multicentre clinical trial.
RecruitingCTIS2024-513958-29-00
Trinity College DublinCardiovascular disorders: Hypertension and Obesity
Start: 2025-04-24Target: 50Updated: 2025-11-10
A Phase 3, Randomized, Active- and Placebo-Controlled, Partially-Blinded Study to Compare the Efficacy and Safety of KAI-9531 Administered Once Weekly Versus Semaglutide and Placebo in Participants Living with Obesity Who Do Not Have Diabetes
Not yet recruitingCTIS2025-523511-11-00
Kailera Therapeutics Inc.Obesity
Target: 126Updated: 2026-04-29
Efficacy and safety of NNC0487-0111 s.c. once-weekly compared to semaglutide s.c. once-weekly in participants with overweight or obesity, and type 2 diabetes (AMAZE 8)
Not yet recruitingCTIS2024-520446-31-00
Novo Nordisk A/Sand type 2 diabetes, Participants with overweight or obesity
Target: 85Updated: 2026-05-15
Impact of Semaglutide in Liver Transplant Candidates with Obesity (SOMAL Study): A Prospective Randomized Study.
Not yet recruitingCTIS2026-526953-32-00
Fundacion Para La Formacion E Investigacion Sanitaria De La Region De MurciaArterial hypertension, Dyslipidaemia, Obesity +1
Target: 50Updated: 2026-10-02

Phase 4

Weight Maintenance in Adolescents With Obesity; Long-Term Treatment With Semaglutide s.c. 2.4 mg Once-weekly
Active, not recruitingCTIS2023-508055-40-00
Novo Nordisk A/SObesity
Start: 2025-02-18Target: 309Updated: 2025-12-14
The GOAL study: GLP-1 receptor agonist treatment for Adolescents with Obesity secondary to Antipsychotic Medication - A feasibility study
RecruitingCTIS2024-517471-21-02
Clinical Pharmacology, Department ofAdipositas
Start: 2025-06-24Target: 34Updated: 2025-05-02
Waiting on Atrial fibrillation Intervention Therapy (WAIT) Study
Not yet recruitingCTIS2025-524182-25-00
Karolinska University HospitalAtrial fibrillation
Target: 200Updated: 2025-12-17