Watchful waiting

OTHER8 trials

Sponsors

BioNTech SE, University of Pennsylvania, Christine Mauz-Körholz, Charite University, Berlin, Germany, UMC Utrecht

Conditions

Active SurveillanceAtrial fibrillationDiseases of Mitral ValveHeart; Disease, Mitral(Valve)Idiopathic Acute PancreatitisIncisional HerniaLung Ground-glass OpacitiesLymphoma

Phase 2

A multi-site, open-label, Phase II, randomized, controlled trial to compare the efficacy of RO7198457 versus watchful waiting in resected, Stage II (high risk) and Stage III colorectal cancer patients who are ctDNA positive following resection

RecruitingCTIS2023-509516-28-00

BioNTech SEStage II/Stage III rectal cancer or Stage II (high risk)/Stage III colon cancer

Start: 2021-02-22Target: 188Updated: 2025-11-06

Phase 4

Surgery Alone or With CYC VBL and PRED or CVP Alone in Stage IA or IIA Nodular Lymphocyte-Predominant Hodgkin Lymphoma

CompletedNCT01088750

Christine Mauz-KörholzLymphoma

Start: 2009-11-01End: 2023-10-31Updated: 2023-12-13

Unknown Phase

Childhood Adenotonsillectomy Study for Children With OSAS

CompletedNCT00560859

University of PennsylvaniaObstructive Sleep Apnea, Snoring

Start: 2007-10-31End: 2012-06-30Updated: 2015-12-15

Watchful Waiting Versus Repair of Oligosymptomatic Incisional Hernias

CompletedNCT01349400

Charite University, Berlin, GermanyIncisional Hernia

Start: 2011-11-30End: 2021-06-30Updated: 2024-02-13

The Dutch Asymptomatic Mitral Regurgitation Trial

TerminatedNCT01708265

UMC UtrechtDiseases of Mitral Valve, Heart; Disease, Mitral(Valve), Mitral Valve Insufficiency

Start: 2013-02-28End: 2021-02-28Updated: 2016-11-23

Device-based Rate Versus Rhythm Control in Symptomatic Recent-onset Atrial Fibrillation (RACE 9 OBSERVE-AF)

RecruitingNL-OMON22526

MUMC+Atrial fibrillation

Start: 2020-11-16Target: 490Updated: 2024-02-28

Surveillance for Multifocal GGNs

RecruitingNCT06097910

Fudan UniversityActive Surveillance, Lung Ground-glass Opacities

Start: 2023-11-01End: 2036-11-01Target: 370Updated: 2025-01-31

Preventing Recurrent 'Idiopathic' Acute Pancreatitis Through Laparoscopic Cholecystectomy (PICUS-2)

RecruitingNCT06391359

M.G. BesselinkIdiopathic Acute Pancreatitis

Start: 2023-07-30End: 2026-07-30Target: 262Updated: 2024-04-30

Related Papers

Pathophysiological Traits in Pediatric Obstructive Sleep Apnea. Associations with Patient Characteristics and Responses to Therapy: A Secondary Analysis of the CHAT Clinical Trial.

2025-12-011 citations

Active Surveillance of Multifocal Ground-Glass Opacities: Results of a Prospective Multicenter Trial (ECTOP1021).

2025-09-201 citations

Childhood OSAS and Obesity: Prospective Associations of Anthropometric Markers With Objective Sleep Outcomes in the CHAT Trial

Journal of Sleep Research2025-07-17

Supine position-related obstructive sleep apnea in children: insights from the Childhood Adenotonsillectomy Trial.

2025-06-30

Active surveillance for patients with multifocal ground-glass nodules: protocol of a prospective, multi-center, single-arm trial (ECTOP-1021)

Journal of Thoracic Disease2025-04-012 citations

Association of allergic rhinitis with persistent obstructive sleep apnea: A secondary analysis of the childhood adenotonsillectomy trial.

2024-02-152 citations

Dysphagia Outcomes Before and After Adenotonsillectomy in Children With Obstructive Sleep Apnea

JAMA Otolaryngology–Head & Neck Surgery2023-08-1710 citations

Sleep quality, sleep apnea, and metabolic health in children treated with adenotonsillectomy.

2022-11-241 citations

Neurobehavioral morbidity of pediatric mild sleep-disordered breathing and obstructive sleep apnea

SLEEP2022-02-1251 citations

Evaluation of Nocturnal Enuresis After Adenotonsillectomy in Children With Obstructive Sleep Apnea

JAMA Otolaryngology–Head & Neck Surgery2021-09-0913 citations

Heart rate variability as a potential biomarker of pediatric obstructive sleep apnea resolution

SLEEP2021-09-0816 citations

Predictors of Behavioral Changes After Adenotonsillectomy in Pediatric Obstructive Sleep Apnea

JAMA Otolaryngology–Head & Neck Surgery2020-09-0330 citations

Cyclic alternating pattern in children with obstructive sleep apnea and its relationship with adenotonsillectomy, behavior, cognition, and quality of life

SLEEP2020-08-1023 citations

Sleep apnea diagnosis in children using software-generated apnea-hypopnea index (AHI) derived from data recorded with a single photoplethysmogram sensor (PPG) : Results from the Childhood Adenotonsillectomy Study (CHAT) based on cardiopulmonary coupling analysis.

2020-03-2826 citations

Objective sleep quality and metabolic risk in healthy weight children results from the randomized Childhood Adenotonsillectomy Trial (CHAT).

2019-02-2311 citations

Depressive symptomatology in school-aged children with obstructive sleep apnea syndrome: incidence, demographic factors, and changes following a randomized controlled trial of adenotonsillectomy

SLEEP2018-09-1323 citations

Effect of adenotonsillectomy for childhood obstructive sleep apnea on nocturnal heart rate patterns

SLEEP2018-08-2417 citations

0502 RELATIONSHIP BETWEEN ANTHROPOMETRIC PARAMETERS AND OBSTRUCTIVE SLEEP APNEA IN SCHOOL AGE CHILDREN

SLEEP2017-04-28

Effect of Adenotonsillectomy on Parent-Reported Sleepiness in Children with Obstructive Sleep Apnea

SLEEP2016-10-3138 citations

Associations among Neighborhood, Race, and Sleep Apnea Severity in Children. A Six-City Analysis

Annals of the American Thoracic Society2016-10-2192 citations

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