Watch-and-wait approach

DIAGNOSTIC_TEST2 trials

Sponsors

GERCOR - Multidisciplinary Oncology Cooperative Group, J. W. A. Burger

Conditions

Colon CancerLocally Advanced Rectal Carcinoma

Phase 2

Neoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.

Not yet recruitingNCT06646445

GERCOR - Multidisciplinary Oncology Cooperative GroupColon Cancer

Start: 2025-09-30End: 2029-12-31Target: 60Updated: 2025-06-13

Phase 3

Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer

RecruitingNCT07472868

J. W. A. BurgerLocally Advanced Rectal Carcinoma

Start: 2026-03-16End: 2034-03-02Target: 394Updated: 2026-10-27

Related Papers

A national, multicentre, randomised, controlled, parallel-arms, phase III clinical trial of neoadjuvant FOLFOXIRI and chemoradiotherapy versus neoadjuvant CAPOX/FOLFOX and chemoradiotherapy in patients with high-risk locally advanced rectal cancer: study protocol of the MEND-IT II trial

BMC Cancer2026-05-18