VVZ-149 Injections

DRUG10 trials

Sponsors

Vivozon, Inc., Vivozon Pharmaceutical Inc., Samsung Medical Center

Conditions

Acute PainPain, PostoperativePain, Postoperative / Acute PainPost-Operative Pain

Phase 2

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injections for Post-Operative Pain Following Colorectal Surgery

CompletedNCT02489526

Vivozon, Inc.Post-Operative Pain

Start: 2015-09-28End: 2016-08-15Updated: 2020-08-25

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

CompletedNCT02522598

Vivozon, Inc.Post-Operative Pain

Start: 2015-08-31End: 2016-02-29Updated: 2016-09-29

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

CompletedNCT02844725

Vivozon, Inc.Post-Operative Pain

Start: 2016-06-30End: 2017-02-28Updated: 2017-11-01

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injections for Post-Operative Pain Following Laparoscopic Colorectomy

CompletedNCT02992041

Vivozon, Inc.Post-Operative Pain

Start: 2016-12-27End: 2018-04-26Updated: 2020-08-25

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.

CompletedNCT03347266

Vivozon, Inc.Post-Operative Pain

Start: 2017-12-20End: 2018-07-19Updated: 2019-03-13

Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Postoperative Pain Following Bunionectomy

CompletedNCT03997812

Vivozon, Inc.Pain, Postoperative

Start: 2019-05-23End: 2019-08-21Updated: 2020-08-25

Opiranserin Injections PCA Regimens for Postoperative Pain

CompletedNCT07821307

Samsung Medical CenterPain, Postoperative / Acute Pain

Start: 2025-07-22End: 2026-01-09Updated: 2026-09-15

Phase 3

Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-Operative Pain Following Abdominoplasty

CompletedNCT03997838

Vivozon, Inc.Pain, Postoperative

Start: 2019-05-23End: 2019-08-21Updated: 2020-08-25

Phase 3 Efficacy and Safety Study of VVZ-149 Injections for Postoperative Pain Following Bunionectomy

Vivozon, Inc.Pain, Postoperative

Start: 2020-06-26End: 2021-01-31Target: 300Updated: 2020-07-23

Efficacy and Safety of VVZ-149 Injections in Patients Undergoing Laparoscopic Colectomy

CompletedNCT05764525

Vivozon Pharmaceutical Inc.Acute Pain, Pain, Postoperative

Start: 2021-07-19End: 2022-11-22Updated: 2025-02-20

Related Papers

Reduction of postoperative pain and opioid consumption by VVZ-149, first-in-class analgesic molecule: A confirmatory phase 3 trial of laparoscopic colectomy.

2024-12-198 citations

Exploratory study of VVZ-149, a novel analgesic molecule, in the affective component of acute postoperative pain after laparoscopic colorectal surgery

Journal of Clinical Anesthesia2021-11-1511 citations

Role of VVZ-149, a Novel Analgesic Molecule, in the Affective Component of Pain: Results from an Exploratory Proof-of-Concept Study of Postoperative Pain following Laparoscopic and Robotic-Laparoscopic Gastrectomy

Pain Medicine2021-02-2313 citations

Randomised, double-blind, parallel group, placebo-controlled study to evaluate the analgesic efficacy and safety of VVZ-149 injections for postoperative pain following laparoscopic colorectal surgery

BMJ Open2017-02-018 citations