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Volasertib

DRUG15 trials

Sponsors

Boehringer Ingelheim, University of Ulm, University of Alberta, Anne Beaven, MD, Northwestern University

Conditions

AMLAcute Myeloid Leukemia (AML)CTCLHigh-risk Myelodysplastic Syndrome (MDS)LeukemiaLeukemia, Erythroblastic, AcuteLeukemia, Megakaryoblastic, AcuteLeukemia, Monocytic, Acute

Phase 1

Volasertib in Japanese Patients With Acute Myeloid Leukemia (AML)
CompletedNCT01662505
Boehringer IngelheimLeukemia, Myeloid, Acute
Start: 2012-08-31End: 2015-05-31Updated: 2018-07-30
Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours
CompletedNCT01772563
Boehringer IngelheimNeoplasms
Start: 2013-02-04End: 2021-04-22Updated: 2023-09-01
Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMML
TerminatedNCT01957644
Boehringer IngelheimLeukemia, Myelomonocytic, Chronic, Myelodysplastic Syndromes
Start: 2013-11-06End: 2016-12-16Updated: 2019-02-08
Open Dose Escalating Trial to Determine the Maximum Tolerated Dose in Paediatric Patients With Advanced Cancers for Whom no Therapy is Known
CompletedNCT01971476
Boehringer IngelheimLeukemia, Neoplasms
Start: 2013-10-22End: 2017-01-27Updated: 2018-07-30
Volasertib in Combination With Azacitidine in Japanese Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
CompletedNCT02201329
Boehringer IngelheimLeukemia, Myelomonocytic, Chronic, Myelodysplastic Syndromes
Start: 2014-08-31End: 2015-09-30Updated: 2018-07-30
A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia
WithdrawnNCT02527174
University of AlbertaLeukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute +2
Start: 2016-11-30End: 2018-09-30Updated: 2017-04-05
A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy Failed
WithdrawnNCT02722135
Boehringer IngelheimLeukemia, Myeloid, Acute
Start: 2016-11-30End: 2018-09-30Updated: 2017-01-27
Trial of Volasertib With or Without Azacitidine in Patients With Myelodysplastic Syndromes
TerminatedNCT02721875
Boehringer IngelheimMyelodysplastic Syndromes
Start: 2016-04-28End: 2016-07-29Updated: 2018-08-09
Ph1 Volasertib Plus Romidepsin in R/R PTCL and CTCL
WithdrawnNCT02757248
Anne Beaven, MDCTCL, PTCL
Start: 2016-11-30End: 2016-11-30Updated: 2016-12-01
Volasertib and Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
WithdrawnNCT02861040
Northwestern UniversityRecurrent Adult Acute Lymphoblastic Leukemia, Refractory Adult Acute Lymphoblastic Leukemia
Start: 2016-08-31Updated: 2016-12-15
Study of Volasertib and Belinostat in Patients With Relapsed and Refractory Aggressive B-cell and T-cell Lymphomas
WithdrawnNCT02875002
Yale UniversityLymphoma, Relapsed and Refractory Aggressive B- and T-cell Lymphomas
Start: 2016-10-31End: 2018-09-30Updated: 2017-12-22
Volasertib Combined With Induction Chemotherapy in Acute Myeloid Leukemia
WithdrawnNCT02905994
Massachusetts General HospitalAML
Start: 2016-09-30End: 2017-02-28Updated: 2018-05-04

Phase 2

Phase 3

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