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Vincristine Sulfate 1 mg/ml solution for injection

DRUG8 trials

Sponsors

AbbVie Deutschland GmbH & Co. KG, Fondazione Gimema Franco Mandelli Onlus, Charite Universitaetsmedizin Berlin KöR, Pfizer Inc., Centre Leon Berard

Conditions

Acute Lymphoblastic Leukemia (ALL)Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.Diffuse Large B-Cell Lymphoma (DLBCL)Follicular LymphomaLarge B-cell LymphomaNewly diagnosed with an intracranial or spinal ependymoma (all WHO grades) including ependymoma variants: cellularPatients with High Risk NeuroblastomaRelapsed Acute Lymphoblastic Leukemia (ALL)

Phase 2

Phase 3

A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination with R-CHOP Compared to R-CHOP in Subjects with Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (EPCORE DLBCL-2)
RecruitingCTIS2023-505277-32-00
AbbVie Deutschland GmbH & Co. KGDiffuse Large B-Cell Lymphoma (DLBCL)
Start: 2023-01-26Target: 435Updated: 2025-12-11
A Phase 3, Multicenter, Randomized, Open-Label Trial to Evaluate the Safety and Efficacy of Epcoritamab + Rituximab and Lenalidomide (R2) compared to Chemoimmunotherapy in Previously Untreated Follicular Lymphoma (EPCORE™FL-2)
Active, not recruitingCTIS2023-506906-38-00
AbbVie Deutschland GmbH & Co. KGFollicular Lymphoma
Start: 2024-05-23Target: 357Updated: 2026-01-20
Newly Diagnosed Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL). Sequential Treatment with Ponatinib and the Bispecific Monoclonal Antibody Blinatumomab vs Chemotherapy and Imatinib. ALL2820
Active, not recruitingCTIS2023-508968-30-00
Fondazione Gimema Franco Mandelli OnlusAdult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.
Start: 2021-09-08Target: 236Updated: 2024-10-01
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) “Randomized, international and multicentric phase 3 study that evaluates and compares 2 treatment strategies in 3 therapeutic phases (induction, high-dose chemotherapy and radiotherapy) for patients with high-risk neuroblastoma and introduces chemoimmunotherapy for patients with insufficient metastatic response after induction chemotherapy
RecruitingCTIS2024-514917-36-00
Institut Gustave RoussyPatients with High Risk Neuroblastoma
Start: 2024-11-21Target: 719Updated: 2025-01-17
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 - A Randomized Phase III Study Conducted by the Resistant Disease Committee of the International BFM Study Group - IntReALL BCP 2020
Not yet recruitingCTIS2023-509392-17-00
Charite Universitaetsmedizin Berlin KöRRelapsed Acute Lymphoblastic Leukemia (ALL)
Target: 765Updated: 2025-12-15
A Phase III, Multicentre, Open-Label, Randomised Study Evaluating the Efficacy and Safety of R-mini-CHOP x2 followed by AZD0486 versus R-mini-CHOP x6 in Elderly or Unfit Participants with Newly Diagnosed Large B-cell Lymphoma (SOUNDTRACK-D2)
Not yet recruitingCTIS2025-522029-37-00
AstraZeneca ABLarge B-cell Lymphoma
Target: 14Updated: 2026-01-30