Veritikug (UPB-101) matching solution for subcutaneous injection with no active treatment
Sponsors
Upstream Bio Inc.
Conditions
Chronic Rhinosinusitis with Nasal PolypsSevere Asthma
Phase 2
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Assess the Efficacy and Safety of Verekitug (UPB-101) in Participants with Chronic Rhinosinusitis with Nasal Polyps on a Background of Nasal Corticosteroids (VIBRANT)
CompletedCTIS2023-508231-31-00
Start: 2024-07-24End: 2025-07-11Target: 45Updated: 2025-07-01
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center, Dose-ranging Study to Evaluate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants with Severe Asthma (VALIANT)
Active, not recruitingCTIS2023-507410-27-00
Start: 2024-06-19Target: 182Updated: 2025-09-29
A Long-Term Extension Study to Evaluate Safety and Efficacy of Verekitug (UPB-101) in Adult Participants with Severe Asthma who Completed the VALIANT Trial
RecruitingCTIS2024-519469-23-00
Start: 2025-10-20Target: 123Updated: 2026-01-26