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Verdiperstat

DRUG5 trials

Sponsors

Biohaven Pharmaceuticals, Inc., Merit E. Cudkowicz, MD, Brigham and Women's Hospital, Peter Ljubenkov, MD

Conditions

Amyotrophic Lateral SclerosisMultiple System AtrophyMultiple System Atrophy (MSA) With Orthostatic HypotensionMultiple System Atrophy, Cerebellar VariantMultiple System Atrophy, Parkinson Variant (Disorder)Semantic Dementia

Early Phase 1

Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients
CompletedNCT04616456
Brigham and Women's HospitalMultiple System Atrophy, Multiple System Atrophy, Cerebellar Variant, Multiple System Atrophy (MSA) With Orthostatic Hypotension +1
Start: 2020-12-30End: 2022-01-30Updated: 2022-08-19

Phase 1

Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology
RecruitingNCT05184569
Peter Ljubenkov, MDSemantic Dementia
Start: 2022-04-14End: 2026-09-30Target: 64Updated: 2025-10-15

Phase 2

HEALEY ALS Platform Trial - Master Protocol
RecruitingNCT04297683
Merit E. Cudkowicz, MDAmyotrophic Lateral Sclerosis
Start: 2020-06-14End: 2028-08-01Target: 1500Updated: 2026-03-27
HEALEY ALS Platform Trial - Regimen B Verdiperstat
CompletedNCT04436510
Merit E. Cudkowicz, MDAmyotrophic Lateral Sclerosis
Start: 2020-07-28End: 2022-12-06Updated: 2023-06-12

Phase 3

Study of BHV-3241 in Participants With Multiple System Atrophy
CompletedNCT03952806
Biohaven Pharmaceuticals, Inc.Multiple System Atrophy
Start: 2019-07-29End: 2022-06-30Updated: 2023-09-29

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