VER-01

DRUG7 trials

Sponsors

Vertanical GmbH

Conditions

Chronic Non-specific Low Back PainFor the treatment of patients with chronic non-specific low back pain when drug treatment is indicated and previous optimised treatments with non-opioid analgesics have not led to sufficient pain relief or were unsuitable due to contraindications or intolerance.HealthyLumbosacral Radiculopathy

Phase 1

Single and Multiple Dose Study of VER-01 in Healthy Volunteers

CompletedNCT04930809

Vertanical GmbHHealthy

Start: 2021-11-25End: 2022-07-11Updated: 2022-07-14

Food Effect Study of VER-01 in Healthy Volunteers

CompletedNCT04930796

Vertanical GmbHHealthy

Start: 2022-08-10End: 2022-11-24Updated: 2022-11-28

Phase 2

Multicenter, double-blind, randomized, placebo-controlled, dose-response trial with the full-spectrum Cannabis Extract VER-01 in patients with chronic non-specific low back pain

CompletedCTIS2023-507358-34-00

Vertanical GmbHFor the treatment of patients with chronic non-specific low back pain when drug treatment is indicated and previous optimised treatments with non-opioid analgesics have not led to sufficient pain relief or were unsuitable due to contraindications or intolerance.

Start: 2024-02-13End: 2025-07-31Target: 767Updated: 2025-08-15

Dose-Response Characterization of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain

CompletedNCT06475001

Vertanical GmbHChronic Non-specific Low Back Pain

Start: 2024-06-28End: 2025-07-31Updated: 2025-08-11

Phase 3

Efficacy and Safety of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain

CompletedNCT04940741

Vertanical GmbHChronic Non-specific Low Back Pain

Start: 2021-07-07End: 2024-03-26Updated: 2024-04-08

Comparison of VER-01 to Opioids in Patients With Chronic Non-specific Low Back Pain

CompletedNCT05610813

Vertanical GmbHChronic Non-specific Low Back Pain

Start: 2023-06-08End: 2024-10-18Updated: 2024-11-25

Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy

Not yet recruitingNCT06956014

Vertanical GmbHLumbosacral Radiculopathy

Start: 2026-09-01End: 2028-09-01Target: 810Updated: 2026-06-25

Related Papers

VER-01 Shows Enhanced Gastrointestinal Tolerability, Superior Pain Relief, and Improved Sleep Quality Compared to Opioids in Treating Chronic Low Back Pain: A Randomized Phase 3 Clinical Trial

Pain and Therapy2025-09-30

Full-spectrum extract from Cannabis sativa DKJ127 for chronic low back pain: a phase 3 randomized placebo-controlled trial

Nature Medicine2025-09-294 citations