VEGF Trap-Eye (BAY86-5321)

BIOLOGICAL3 trials

Sponsors

Bayer

Conditions

Diabetes MellitusMacular EdemaMyopia, Pathological

Phase 3

VEGF Trap-Eye in Choroidal Neovascularization Secondary to Pathologic Myopia (mCNV)

CompletedNCT01249664

BayerMyopia, Pathological

Start: 2010-12-31End: 2013-08-31Updated: 2014-05-05

Intravitreal Aflibercept Injection in Vision Impairment Due to DME

CompletedNCT01331681

BayerDiabetes Mellitus, Macular Edema

Start: 2011-05-09End: 2015-03-30Updated: 2023-11-27

Japanese Safety Study of VEGF Trap-Eye in DME (Diabetic Macular Edema)

CompletedNCT01512966

BayerMacular Edema

Start: 2012-01-31End: 2013-09-30Updated: 2014-10-09

Related Papers

Clinically Meaningful Change Estimates for the National Eye Institute Visual Function Questionnaire-25 in Patients With Diabetic Macular Edema.

2024-12-01

Proliferative Diabetic Retinopathy Events in Patients With Diabetic Macular Edema: Post Hoc Analysis of VISTA and VIVID Trials

Journal of VitreoRetinal Diseases2022-06-042 citations

Functional outcomes of sustained improvement on Diabetic Retinopathy Severity Scale with intravitreal aflibercept in the VISTA and VIVID trials

Eye2022-04-192 citations

Impact of Baseline Central Retinal Thickness on Outcomes in the VIVID-DME and VISTA-DME Studies

Journal of Ophthalmology2018-01-0112 citations

Impact of baseline Diabetic Retinopathy Severity Scale scores on visual outcomes in the VIVID-DME and VISTA-DME studies

British Journal of Ophthalmology2017-10-1923 citations

Intravitreal Aflibercept Injection in Eyes With Substantial Vision Loss After Laser Photocoagulation for Diabetic Macular Edema

JAMA Ophthalmology2016-12-2214 citations

Initiation of intravitreal aflibercept injection treatment in patients with diabetic macular edema: a review of VIVID-DME and VISTA-DME data.

2016-07-1128 citations

Intravitreal Aflibercept Has Long-Term Benefits in Treatment of DME

MD Conference Express2014-12-01

Visual outcomes following intravitreal aflibercept in patients with myopic choroidal neovascularisation

Acta Ophthalmologica2014-08-20

Prognostic factors in myopic choroidal neovascularisation

Acta Ophthalmologica2014-08-20